Is 5-Amino-1MQ a peptide?

No. 5-Amino-1MQ (5-amino-1-methylquinolinium) is a small molecule, not a peptide, despite frequently being sold and grouped commercially with peptides. It is a chemical inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), with no amino-acid sequence.

What is 5-Amino-1MQ used for?

It is marketed for weight loss and metabolic support, framed around NNMT and NAD+ metabolism. Those marketed uses are not approved anywhere and are not backed by human evidence. It is sold only as a research chemical and is not a recognised dietary supplement.

Are there human studies on 5-Amino-1MQ?

No. There are no published human clinical trials of 5-Amino-1MQ, and no peer-reviewed human efficacy or safety data exist. All controlled evidence comes from rodents and cell culture. Users discussing it online commonly note this absence themselves.

Human safety is unknown. Because it is unapproved and untested in people, its adverse-effect profile, long-term risks, and drug interactions are not established, and safety observations exist only from short-term animal studies. This information is educational and not a substitute for professional medical advice.

Is 5-Amino-1MQ legal or approved?

It is not approved for human use in any jurisdiction and is not a recognised dietary supplement, so products marketing it as one are misdescribing its status. It is sold as a research chemical, and its legal position varies by country.

Where can I buy 5-Amino-1MQ and compare vendors?

Use the vendor comparison on this page. It shows only checked, product-specific links and identifies vendor claims, independent documentation and affiliate relationships separately. Availability and legal status can vary by country.

Metabolic

Buy 5-Amino-1MQ – Vendors, Prices, Testing and Evidence

Buy 5-Amino-1MQ

Also known as: 5-amino-1-methylquinolinium · 5A1MQ · NNMT inhibitor

Evidence grade C — Early / PreclinicalRisk flag

Short answer

A small-molecule NNMT inhibitor — not a peptide — investigated for fat metabolism and weight. Evidence is preclinical only, from cell and rodent studies, with no published human trials.

Where can you buy 5-Amino-1MQ?

Crystal Peptides. The table lists only product-specific offers that were checked and for which a real destination exists. Missing prices, quantities, stock and laboratory details are not inferred.

What is known?

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). It is not a peptide, despite frequently being sold alongside peptides. It is marketed for weight loss and metabolic support and is not approved for human use.

What is not established?

There are no published human clinical trials of 5-Amino-1MQ. No peer-reviewed human efficacy or safety data exist; all controlled evidence is from rodents and cell culture.

Safety

Human safety is unknown. Because it is unapproved and untested in people, its adverse-effect profile, long-term risks, and drug interactions are not established.

Regulatory status

Not approved for human use in any jurisdiction and not a recognised dietary supplement. A small molecule, not a peptide. Sold only as a 'research chemical.'

Not medical advice. This educational reference is not diagnosis, treatment, prescribing, dosing or emergency guidance. Consult a qualified professional before making health-related decisions.

Regulatory or safety concern: This substance may be unapproved for human use, affect the hormonal system, or be subject to regulator or anti-doping restrictions. Check the cited evidence and rules in your jurisdiction.

Vendor comparison

Buy 5-Amino-1MQ: compare vendors

The table lists only product-specific offers that were checked and for which a real destination exists. Missing prices, quantities, stock and laboratory details are not inferred.

Vendor	Product	Documentation	Shipping	Checked	Action
Crystal Peptides Code PEPTIDES10 −10% · discount code details Sponsored	5-Amino-1MQ research product	Vendor-supplied data COA stated as available Not independently documented	Europe See the localized country store	Jul 18, 2026	View at vendor

Crystal Peptides

5-Amino-1MQ research product

Code PEPTIDES10 −10% · discount code details

What is it?

Research and evidence

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small molecule, not a peptide. That distinction matters, because it is routinely sold and discussed alongside peptides and is widely assumed to be one. Chemically it is an inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme in NAD+ and methylation metabolism that is reported to be elevated in obese adipose tissue. It is marketed for weight loss and metabolic support. It is not approved for human use in any jurisdiction and is not a recognised dietary supplement; it is sold only as a research chemical. peptides.cx catalogues it under Metabolic with an evidence grade of C.

The evidence is preclinical, and that is the whole picture. In diet-induced obese mice, a lead NNMT inhibitor, 5-amino-1MQ, reduced body weight and white-adipose mass and lowered plasma cholesterol without changing food intake in that study. The proposed explanation is that inhibiting NNMT shifts cellular energy metabolism and reduces fat-cell size. Those are real published findings, and they come entirely from rodents and cell culture. There are no published human clinical trials of 5-Amino-1MQ: no peer-reviewed human efficacy data, no human safety data, nothing that would let anyone say what it does in a person. Metabolic results in mice have a long history of not carrying over to humans, so the honest answer to whether this translates is that nobody knows.

Human safety is unknown for the same reason efficacy is unknown, which is that nobody has published a trial. Its adverse-effect profile, long-term risks, and drug interactions are not established, and the only safety observations available come from short-term animal studies. Marketing that frames it as a supplement does not change its regulatory position: it has no approved status and no recognised dietary-supplement status in the EU or US. If you see 5-Amino-1MQ described as a peptide, that is a factual error, and a reasonable reason to be sceptical of the rest of the description. This page is an educational reference summarising what the science does and does not show; it is not medical advice, and it does not provide dosing, protocols, or sourcing guidance.

Evidence grade: C

There are no published human clinical trials of 5-Amino-1MQ. No peer-reviewed human efficacy or safety data exist; all controlled evidence is from rodents and cell culture. In diet-induced obese mice, a lead NNMT inhibitor (5-amino-1MQ) reduced body weight and white-adipose mass and lowered plasma cholesterol without changing food intake in that study. The findings are preclinical and have not been confirmed in humans.

Human evidence

There are no published human clinical trials of 5-Amino-1MQ. No peer-reviewed human efficacy or safety data exist; all controlled evidence is from rodents and cell culture.

Animal and preclinical evidence

In diet-induced obese mice, a lead NNMT inhibitor (5-amino-1MQ) reduced body weight and white-adipose mass and lowered plasma cholesterol without changing food intake in that study. The findings are preclinical and have not been confirmed in humans.

Proposed mechanisms

Inhibits NNMT, an enzyme in NAD+/methylation metabolism reported to be elevated in obese adipose tissue
In preclinical models, NNMT inhibition is associated with reduced fat-cell size and body weight, proposed to work by shifting cellular energy metabolism
These mechanisms come from animal and cell studies; whether they translate to humans is unknown

Safety concerns and known side effects

Human safety is unknown. Because it is unapproved and untested in people, its adverse-effect profile, long-term risks, and drug interactions are not established.

No human adverse-effect profile has been established; safety observations come only from short-term animal studies

Regulatory status

Not approved for human use in any jurisdiction and not a recognised dietary supplement. A small molecule, not a peptide. Sold only as a 'research chemical.'

Frequently asked questions about 5-Amino-1MQ

Is 5-Amino-1MQ a peptide?: No. 5-Amino-1MQ (5-amino-1-methylquinolinium) is a small molecule, not a peptide, despite frequently being sold and grouped commercially with peptides. It is a chemical inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), with no amino-acid sequence.
What is 5-Amino-1MQ used for?: It is marketed for weight loss and metabolic support, framed around NNMT and NAD+ metabolism. Those marketed uses are not approved anywhere and are not backed by human evidence. It is sold only as a research chemical and is not a recognised dietary supplement.
Does 5-Amino-1MQ work for weight loss?: This is unknown in humans. In diet-induced obese mice, the NNMT inhibitor reduced body weight and white-adipose mass and lowered plasma cholesterol without changing food intake in that study. Those results are preclinical and have never been confirmed in people, and rodent metabolic findings often fail to translate.
Are there human studies on 5-Amino-1MQ?: No. There are no published human clinical trials of 5-Amino-1MQ, and no peer-reviewed human efficacy or safety data exist. All controlled evidence comes from rodents and cell culture. Users discussing it online commonly note this absence themselves.
Is 5-Amino-1MQ safe?: Human safety is unknown. Because it is unapproved and untested in people, its adverse-effect profile, long-term risks, and drug interactions are not established, and safety observations exist only from short-term animal studies. This information is educational and not a substitute for professional medical advice.
Is 5-Amino-1MQ legal or approved?: It is not approved for human use in any jurisdiction and is not a recognised dietary supplement, so products marketing it as one are misdescribing its status. It is sold as a research chemical, and its legal position varies by country.
Where can I buy 5-Amino-1MQ and compare vendors?: Use the vendor comparison on this page. It shows only checked, product-specific links and identifies vendor claims, independent documentation and affiliate relationships separately. Availability and legal status can vary by country.

Common discussion areas

Marketed and discussed for fat loss and 'metabolic optimisation,' often framed around NAD+ and NNMTFrequently grouped commercially with peptides even though it is a small moleculeUsers commonly note the absence of human data

Sources

Editorial review and transparency

Written by: peptides.cx Editorial Team
Scientific reviewer: No named medical reviewer is currently assigned
Last editorial review: July 18, 2026
Last vendor check: July 18, 2026
Review method: Source review, claim verification, vendor-data separation and regulatory-context review.
Commercial disclosure and conflicts: Vendor relationships do not determine evidence or safety ratings. No named reviewer conflict is recorded because no named reviewer is assigned.

Editorial policy →Evidence grade →Vendor methodology →

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